(2-Carboxyethyl)-beta-cyclodextrin sodium salt,

Analysis Note

average degree of substitution, DS ~3

Application

Cyclodextrins (CD) are cyclic oligosaccharides composed of D-glucose units connected via A(1→4) glycosidic bonds. Common cyclodextrins contain six (A-CD); seven (β-CD) or eight (gamma-CD) D-glucose units. Cyclodextrins are sometimes derivitized through esterification at positions two, three and/or six.(2-Carboxyethyl)-β-cyclodextrin and other negative charge derivitized cyclodextrins are used in chiral recognition and resolution of cationic racemic mixtures of enantiomers using capillary electrophoresis.

(2-Carboxyethyl)-β-cyclodextrin sodium salt may be used: As a chiral selector for the enantioseparation of cinacalcet impurities and fenamiphos pesticide by capillary zone electrophoresis and ³¹P nuclear magnetic resonance spectroscopy (³¹P NMR), respectively.To form an inclusion complex with carvacrol for subsequent use in the antibacterial multilayer construction with chitosan, loaded onto poly(L-lactic acid) (PLLA).

General description

(2-Carboxyethyl)-β-cyclodextrin sodium is a derivative of β-cyclodextrin, typically used to enhance the properties of the latter such as stability and water solubility. β-cyclodextrin has garnered increased research attention due to its potential application as host-guest inclusion complex used in the pharmaceutical industry and as antibacterial material utilized in food and pharmacy.